PREPARE Challenge - Phase 2: Model Arena (Acoustic Track)

Advance algorithms and analytic approaches for early prediction of Alzheimer's disease and related dementias based on voice recordings, with an emphasis on explainability of predictions. [Model Arena - Acoustic Track] #health

$130,000 in prizes
Completed dec 2024
401 joined

About the data

The data for the Acoustic Track of PREPARE Phase 2 comes from DementiaBank. The potential of these datasets for early prediction of Alzheimer's Disease and Alzheimer's Disease Related Dementias was identified by the 1st place winners of Phase 1 of the PREPARE Challenge.

The dataset is a collection of speech samples from individuals diagnosed with cognitive decline as well as healthy controls. Data was collected via structured clinical interviews, either over the phone or in person. The cognitive status of each individual was diagnosed based on interviews, cognitive tests, and language-based tasks, including verbal fluency, sentence construction, picture descriptions, story recall, and conversational interactions.

Each individual is given one of three cognitive status: healthy control, mild cognitive impairment (MCI), or advanced decline. MCI is an early indicator of cognitive decline. While MCI does not always progress to Alzheimer's, MCI is an extremely useful flag for early detection of AD/ADRD.

Cognitive screenings are time intensive and difficult to perform. This competition seeks to identify acoustic biomarkers in speech that may serve as early indicators of AD/ADRD. The ability to flag high-risk individuals based on vocal characteristics has the potential to save time and expand access to cognitive screenings. For example, screening for AD/ADRD in telehealth visits could catch AD/ADRD earlier in hard-to-reach populations and improve treatment.

About the sponsor and challenge

The National Institute of Aging (NIA), one of the 27 Institutes and Centers of the National Institute of Health (NIH), leads a broad scientific effort to understand the nature of aging and to extend the healthy, active years of life. NIA is the primary Federal agency supporting and conducting Alzheimer's disease research.

This challenge is a Eureka Prize Competition, and is aligned with the objectives of the 42 U.S.C. 283q, which calls on NIH to support challenges in areas of biomedical science that could: 1) realize significant advancements and 2) improve health outcomes in human diseases and conditions, particularly with respect to human diseases and conditions for which public and private investment in research is disproportionately small relative to Federal Government expenditures on prevention and treatment activities, that are serious and represent a significant disease burden in the United States, or for which there is potential for significant return on investment to the United States.

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